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SAR1B

Description secretion associated Ras related GTPase 1B
Image No pdb structure
GO Annotations Cellular Component
  • Endoplasmic Reticulum Membrane
  • Cytosol
  • ER To Golgi Transport Vesicle Membrane
  • COPII Vesicle Coat
  • Golgi Cisterna Membrane
  • Endoplasmic Reticulum Exit Site
Molecular Function
  • GTPase Activity
  • Protein Binding
  • GTP Binding
  • Metal Ion Binding
Biological Process
  • Antigen Processing And Presentation Of Peptide Antigen Via MHC Class I
  • Regulation Of COPII Vesicle Coating
  • Intracellular Protein Transport
  • Endoplasmic Reticulum To Golgi Vesicle-mediated Transport
  • Vesicle Organization
  • Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class II
  • COPII Vesicle Coating
  • Membrane Organization
  • Positive Regulation Of Protein Exit From Endoplasmic Reticulum
Pathways
  • Regulation of cholesterol biosynthesis by SREBP (SREBF)
  • COPII-mediated vesicle transport
  • MHC class II antigen presentation
  • Cargo concentration in the ER
  • Chylomicron assembly
  • Antigen Presentation: Folding, assembly and peptide loading of class I MHC
Drugs
  • Guanosine-5'-Diphosphate
Diseases
  • Chylomicron retention disease (CRD); Anderson disease
GWAS
  • Bipolar disorder ( 31043756)
Novel Interacting Genes 1 novel interacting genes: JADE2
Interacting Genes 3 interacting genes: CIDEB CREB3 TMEM14B
Entrez ID 51128
HPRD ID 09647
Ensembl ID ENSG00000152700
Uniprot IDs Q9Y6B6
PDB IDs
Enriched GO Terms of Interacting Partners?
Tagcloud ?

© Madhavi K. Ganapathiraju 2012-2025