OPRL1

Description		opioid related nociceptin receptor 1
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GO Annotations	Cellular Component	Plasma Membrane Integral Component Of Plasma Membrane Cytoplasmic Vesicle Neuron Projection
	Molecular Function	Nociceptin Receptor Activity G Protein-coupled Receptor Activity Protein Binding Peptide Binding Neuropeptide Binding
	Biological Process	G Protein-coupled Receptor Signaling Pathway Adenylate Cyclase-inhibiting G Protein-coupled Receptor Signaling Pathway Neuropeptide Signaling Pathway Sensory Perception Behavior Sensory Perception Of Pain Opioid Receptor Signaling Pathway Positive Regulation Of Cytosolic Calcium Ion Concentration Involved In Phospholipase C-activating G Protein-coupled Signaling Pathway
Pathways		Peptide ligand-binding receptors G alpha (i) signalling events
Drugs		Buprenorphine Etorphine Epicept NP-1
Diseases
GWAS		Cerebrospinal AB1-42 levels in normal cognition ( 29274321) HDL cholesterol levels ( 32203549) LDL peak particle diameter (total fat intake interaction) ( 26112879) Lymphocyte counts ( 32888494) Mean corpuscular hemoglobin ( 32888494) Mean corpuscular volume ( 32888494 27863252) Mean reticulocyte volume ( 32888494) Mean spheric corpuscular volume ( 32888494) Medication use (HMG CoA reductase inhibitors) ( 31015401) Metabolic syndrome ( 31589552) Monocyte count ( 32888494) Triglyceride levels ( 32203549 32154731)
Interacting Genes		10 interacting genes: CERS6 DNAJC30 GNA14 GPRASP1 HLA-C OPRM1 PLLP PNOC RGS19 SLC31A2
Entrez ID		4987
HPRD ID		03971
Ensembl ID		ENSG00000125510
Uniprot IDs		A0A5F9ZI64 P41146 Q8IXB0
PDB IDs		4EA3 5DHG 5DHH
Enriched GO Terms of Interacting Partners?
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