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NPR1
Description
natriuretic peptide receptor 1
Image
No pdb structure
GO Annotations
Cellular Component
Plasma Membrane
Integral Component Of Membrane
Receptor Complex
Molecular Function
Peptide Receptor Activity
Guanylate Cyclase Activity
Protein Kinase Activity
ATP Binding
GTP Binding
G Protein-coupled Peptide Receptor Activity
Natriuretic Peptide Receptor Activity
Peptide Hormone Binding
Protein Kinase Binding
Hormone Binding
Biological Process
CGMP Biosynthetic Process
Protein Phosphorylation
Signal Transduction
Cell Surface Receptor Signaling Pathway
Receptor Guanylyl Cyclase Signaling Pathway
G Protein-coupled Receptor Signaling Pathway
Body Fluid Secretion
Regulation Of Blood Pressure
Positive Regulation Of CGMP-mediated Signaling
Negative Regulation Of Angiogenesis
CGMP-mediated Signaling
Negative Regulation Of Cell Growth
Positive Regulation Of Urine Volume
Positive Regulation Of Renal Sodium Excretion
Dopamine Metabolic Process
Regulation Of Vascular Permeability
Negative Regulation Of Smooth Muscle Cell Proliferation
Blood Vessel Diameter Maintenance
Regulation Of Cardiac Conduction
Pathways
Physiological factors
Drugs
Nitroprusside
Nitroglycerin
Isosorbide dinitrate
Amyl Nitrite
Erythrityl tetranitrate
Nesiritide
Ularitide
Diseases
GWAS
Mean arterial pressure (
27618448
)
Systolic blood pressure (
27618448
)
Interacting Genes
7 interacting genes:
ATF7IP
MTDH
NPPA
NPPB
NPPC
PRKG1
UBE2D2
Entrez ID
4881
HPRD ID
00165
Ensembl ID
ENSG00000169418
Uniprot IDs
A0A140VJE6
P16066
PDB IDs
Enriched GO Terms of Interacting Partners
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