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NPHS1

Description NPHS1 adhesion molecule, nephrin
Image
GO Annotations Cellular Component
  • Plasma Membrane
  • Integral Component Of Plasma Membrane
  • Cell-cell Junction
  • Focal Adhesion
  • Slit Diaphragm
  • Cell Projection
  • Extracellular Exosome
Molecular Function
  • Protein Binding
  • Myosin Binding
  • Cell Adhesion Molecule Binding
Biological Process
  • Cell Adhesion
  • JNK Cascade
  • Skeletal Muscle Tissue Development
  • Myoblast Fusion
  • Excretion
  • Positive Regulation Of Actin Filament Polymerization
  • Glomerular Basement Membrane Development
  • Protein Localization To Synapse
  • Regulation Of Excretion
  • Glomerular Visceral Epithelial Cell Development
  • Cell-cell Adhesion
Pathways
  • Nephrin family interactions
  • Nephrin family interactions
Drugs
Diseases
  • Nephrotic syndrome and focal segmental glomerulosclerosis
GWAS
Interacting Genes 11 interacting genes: CASK CD2AP FYN IQGAP1 KIRREL1 LYN NCK1 NCK2 NPHS2 SRC YES1
Entrez ID 4868
HPRD ID 04094
Ensembl ID ENSG00000161270
Uniprot IDs O60500
PDB IDs 4ZRT
Enriched GO Terms of Interacting Partners?
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