ABCC1

Description		ATP binding cassette subfamily C member 1
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GO Annotations	Cellular Component	Plasma Membrane Integral Component Of Plasma Membrane Basal Plasma Membrane Membrane Basolateral Plasma Membrane Apical Plasma Membrane Lateral Plasma Membrane Extracellular Exosome
	Molecular Function	ATP Binding ABC-type Xenobiotic Transporter Activity ABC-type Vitamin B12 Transporter Activity ABC-type Glutathione S-conjugate Transporter Activity Efflux Transmembrane Transporter Activity ATPase Activity ATPase-coupled Lipid Transmembrane Transporter Activity Glutathione Transmembrane Transporter Activity ATPase-coupled Transmembrane Transporter Activity Xenobiotic Transmembrane Transporter Activity Carboxylic Acid Transmembrane Transporter Activity ABC-type Transporter Activity
	Biological Process	Leukotriene Metabolic Process Cobalamin Metabolic Process Cobalamin Transport Glutathione Transmembrane Transport Response To Drug Xenobiotic Transport Phospholipid Translocation Positive Regulation Of Inflammatory Response Transmembrane Transport Cell Chemotaxis Transepithelial Transport Leukotriene Transport Sphingolipid Translocation Export Across Plasma Membrane Transport Across Blood-brain Barrier Cellular Response To Amyloid-beta Carboxylic Acid Transmembrane Transport
Pathways		Heme degradation Cobalamin (Cbl, vitamin B12) transport and metabolism Synthesis of Leukotrienes (LT) and Eoxins (EX) ABC-family proteins mediated transport
Drugs		ATP Sulfinpyrazone Biricodar Romidepsin Leukotriene C4
Diseases
GWAS		Basophil count ( 32888494) Basophil percentage of white cells ( 32888494) Blood metabolite levels ( 24816252) Blood metabolite ratios ( 24816252) Estimated glomerular filtration rate ( 31152163) Ischemic stroke (undetermined subtype) ( 26708676) Mean corpuscular hemoglobin ( 32888494) Mean corpuscular hemoglobin concentration ( 32888494) Mean reticulocyte volume ( 32888494) Mean spheric corpuscular volume ( 32888494) Multiple myeloma (survival) ( 26198393) Pelvic organ prolapse (moderate/severe) ( 26545240) Psychosis proneness (perceptual aberration scale) ( 28525603) Rate of ventricular enlargement ( 31711042) Red cell distribution width ( 32888494) Response to antiepileptic mood-stabilizing treatment in bipolar disorder ( 32627186) Venous thromboembolism adjusted for sickle cell variant rs77121243-T ( 28203683) White blood cell count (basophil) ( 27863252)
Novel Interacting Genes		1 novel interacting genes: TNFRSF17
Interacting Genes		6 interacting genes: ATP5F1A AZGP1 CSNK2A1 NPM1 NR3C1 TRAF3
Entrez ID		4363
HPRD ID		01153
Ensembl ID		ENSG00000103222
Uniprot IDs		P33527
PDB IDs		2CBZ 4C3Z
Enriched GO Terms of Interacting Partners?
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