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ASCL2
Description
achaete-scute family bHLH transcription factor 2
Image
No pdb structure
GO Annotations
Cellular Component
Chromatin
Nucleus
Cytoplasm
RNA Polymerase II Transcription Regulator Complex
Molecular Function
RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding
RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding
DNA-binding Transcription Factor Activity, RNA Polymerase II-specific
DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific
Protein Dimerization Activity
E-box Binding
Sequence-specific Double-stranded DNA Binding
Biological Process
Negative Regulation Of Transcription By RNA Polymerase II
Response To Hypoxia
Placenta Development
Regulation Of Transcription By RNA Polymerase II
Sensory Organ Development
Negative Regulation Of Schwann Cell Proliferation
Neuron Differentiation
Somatic Stem Cell Population Maintenance
Positive Regulation Of Transcription By RNA Polymerase II
Regulation Of Neurogenesis
Spongiotrophoblast Layer Development
Pathways
Drugs
Diseases
GWAS
Celiac disease (
23936387
)
Malaria (
31844061
)
Type 1 diabetes in high risk HLA genotype individuals (time to event) (
29310926
)
Type 2 diabetes (
25102180
31118516
)
Interacting Genes
3 interacting genes:
CALM1
CALM2
CALM3
Entrez ID
430
HPRD ID
03533
Ensembl ID
ENSG00000183734
Uniprot IDs
Q99929
PDB IDs
Enriched GO Terms of Interacting Partners
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