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MGST1

Description microsomal glutathione S-transferase 1
Image No pdb structure
GO Annotations Cellular Component
  • Nucleus
  • Mitochondrion
  • Mitochondrial Outer Membrane
  • Peroxisomal Membrane
  • Endoplasmic Reticulum
  • Endoplasmic Reticulum Membrane
  • Plasma Membrane
  • Integral Component Of Membrane
  • Azurophil Granule Membrane
  • Apical Part Of Cell
Molecular Function
  • Glutathione Transferase Activity
  • Glutathione Peroxidase Activity
  • Protein Binding
  • Identical Protein Binding
  • Glutathione Binding
Biological Process
  • Xenobiotic Metabolic Process
  • Response To Organonitrogen Compound
  • Response To Lipopolysaccharide
  • Leydig Cell Differentiation
  • Response To Drug
  • Neutrophil Degranulation
  • Cellular Response To Lipid Hydroperoxide
  • Cellular Oxidant Detoxification
  • Glutathione Derivative Biosynthetic Process
Pathways
  • Glutathione conjugation
  • Aflatoxin activation and detoxification
  • Neutrophil degranulation
Drugs
  • Glutathione
  • Glutathione disulfide
Diseases
GWAS
  • Colorectal cancer (aspirin and/or NSAID use interaction) ( 25781442)
  • Household income (MTAG) ( 31844048)
  • Metabolite levels ( 23823483)
  • Visceral fat ( 22589738)
Interacting Genes 8 interacting genes: EGF FXYD3 FZD7 LTC4S NELFB SIGLEC12 TNFRSF10C VIP
Entrez ID 4257
HPRD ID 00705
Ensembl ID ENSG00000008394
Uniprot IDs A0A024RAX2 P10620
PDB IDs
Enriched GO Terms of Interacting Partners?
Tagcloud ?

© Madhavi K. Ganapathiraju 2012-2025