MAOA

Description		monoamine oxidase A
Image
GO Annotations	Cellular Component	Mitochondrion Mitochondrial Outer Membrane Cytosol Integral Component Of Membrane
	Molecular Function	Protein Binding Primary Amine Oxidase Activity
	Biological Process	Cellular Biogenic Amine Metabolic Process Positive Regulation Of Signal Transduction Cytokine-mediated Signaling Pathway Neurotransmitter Metabolic Process Neurotransmitter Catabolic Process Dopamine Catabolic Process
Pathways		Biogenic amines are oxidatively deaminated to aldehydes by MAOA and MAOB Norepinephrine Neurotransmitter Release Cycle Enzymatic degradation of dopamine by COMT Enzymatic degradation of Dopamine by monoamine oxidase Metabolism of serotonin Defective MAOA causes Brunner syndrome (BRUNS) Interleukin-4 and Interleukin-13 signaling
Drugs		Amphetamine Phentermine Procaine Tranylcypromine Phenelzine Minaprine Zonisamide Selegiline Procarbazine Moclobemide Moclobemide Isocarboxazid Ephedra sinica root MMDA 4-Methoxyamphetamine Metamfetamine Pargyline Flavin adenine dinucleotide Clorgiline Nialamide Nomifensine Zimelidine Posizolid CX157 Decyl(dimethyl)phosphine oxide Harmine Pirlindole Toloxatone Brofaromine Flortaucipir F-18
Diseases		Brunner syndrome; MAOA deficiency
GWAS		Smoking behavior ( 19247474)
Interacting Genes		1 interacting genes: NDRG1
Entrez ID		4128
HPRD ID		02400
Ensembl ID		ENSG00000189221
Uniprot IDs		P21397 Q49A63 Q53YE7
PDB IDs		1H8Q 2BXR 2BXS 2Z5X 2Z5Y
Enriched GO Terms of Interacting Partners?
Tagcloud ?