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LAMTOR4

Description late endosomal/lysosomal adaptor, MAPK and MTOR activator 4
Image
GO Annotations Cellular Component
  • Lysosome
  • Lysosomal Membrane
  • Intracellular Membrane-bounded Organelle
  • Ragulator Complex
Molecular Function
  • Guanyl-nucleotide Exchange Factor Activity
  • Protein Binding
  • Molecular Adaptor Activity
Biological Process
  • Cell Cycle Arrest
  • Regulation Of Cell Size
  • Regulation Of Macroautophagy
  • Positive Regulation Of TOR Signaling
  • Regulation Of Catalytic Activity
  • Protein Localization To Lysosome
  • Cellular Response To Amino Acid Stimulus
Pathways
  • Macroautophagy
  • MTOR signalling
  • mTORC1-mediated signalling
  • Energy dependent regulation of mTOR by LKB1-AMPK
  • TP53 Regulates Metabolic Genes
  • Regulation of PTEN gene transcription
  • Amino acids regulate mTORC1
Drugs
Diseases
GWAS
  • Brain morphology (MOSTest) ( 32665545)
  • Refractive error ( 32231278)
  • Subcortical volume (MOSTest) ( 32665545)
Interacting Genes 2 interacting genes: LAMTOR5 USP19
Entrez ID 389541
HPRD ID 17380
Ensembl ID ENSG00000188186
Uniprot IDs A0A087WT92 A0A087WV46 Q0VGL1
PDB IDs 5VOK 5X6U 5X6V 5Y38 5Y39 5Y3A 5YK5 6B9X 6EHP 6EHR 6NZD 6U62 6ULG 6WJ2 6WJ3
Enriched GO Terms of Interacting Partners?
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© Madhavi K. Ganapathiraju 2012-2025