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IMPDH1

Description inosine monophosphate dehydrogenase 1
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GO Annotations Cellular Component
  • Extracellular Region
  • Nucleus
  • Cytoplasm
  • Cytosol
  • Secretory Granule Lumen
  • Azurophil Granule Lumen
  • Ficolin-1-rich Granule Lumen
Molecular Function
  • Nucleotide Binding
  • Nucleic Acid Binding
  • DNA Binding
  • RNA Binding
  • IMP Dehydrogenase Activity
  • Metal Ion Binding
Biological Process
  • GMP Biosynthetic Process
  • GTP Biosynthetic Process
  • Purine Ribonucleoside Monophosphate Biosynthetic Process
  • Neutrophil Degranulation
Pathways
  • Neutrophil degranulation
  • Purine ribonucleoside monophosphate biosynthesis
  • Potential therapeutics for SARS
Drugs
  • NADH
  • Mycophenolate mofetil
  • Ribavirin
  • Mycophenolic acid
  • Mercaptopurine
  • 6-Chloropurine Riboside, 5'-Monophosphate
  • VX-148
  • Taribavirin
Diseases
  • Leber congenital amaurosis (LCR)
  • Retinitis pigmentosa (RP)
GWAS
  • Pelvic organ prolapse ( 32184442)
Interacting Genes 8 interacting genes: DDIT4L GMNN HTRA1 IMPDH2 PIAS2 RAD54L2 RNF4 UBE2I
Entrez ID 3614
HPRD ID 08853
Ensembl ID ENSG00000106348
Uniprot IDs B3KRZ3 P20839 Q6ZNB1
PDB IDs 1JCN
Enriched GO Terms of Interacting Partners?
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© Madhavi K. Ganapathiraju 2012-2025