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HLA-DRB4

Description major histocompatibility complex, class II, DR beta 4
Image No pdb structure
GO Annotations Cellular Component
  • Golgi Membrane
  • Lysosomal Membrane
  • Plasma Membrane
  • ER To Golgi Transport Vesicle Membrane
  • Transport Vesicle Membrane
  • Endocytic Vesicle Membrane
  • Clathrin-coated Endocytic Vesicle Membrane
  • Late Endosome Membrane
  • Trans-Golgi Network Membrane
  • MHC Class II Protein Complex
  • Integral Component Of Lumenal Side Of Endoplasmic Reticulum Membrane
Molecular Function
Biological Process
  • Adaptive Immune Response
  • Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class II
  • T Cell Receptor Signaling Pathway
  • Interferon-gamma-mediated Signaling Pathway
Pathways
  • Downstream TCR signaling
  • Phosphorylation of CD3 and TCR zeta chains
  • Translocation of ZAP-70 to Immunological synapse
  • Generation of second messenger molecules
  • MHC class II antigen presentation
  • PD-1 signaling
  • Interferon gamma signaling
Drugs
  • 1D09C3
  • Coccidioides immitis spherule
Diseases
GWAS
Interacting Genes 3 interacting genes: ASMTL CTAG1B MAGEA6
Entrez ID 3126
HPRD ID 09986
Ensembl ID
Uniprot IDs P13762 X5D2U9
PDB IDs
Enriched GO Terms of Interacting Partners?
Tagcloud ?

© Madhavi K. Ganapathiraju 2012-2025