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GUCA1A

Description guanylate cyclase activator 1A
Image No pdb structure
GO Annotations Cellular Component
  • Photoreceptor Inner Segment
  • Photoreceptor Disc Membrane
  • Cone Photoreceptor Outer Segment
Molecular Function
  • Calcium Ion Binding
  • Protein Binding
  • Calcium Sensitive Guanylate Cyclase Activator Activity
  • Guanylate Cyclase Regulator Activity
Biological Process
  • Signal Transduction
  • Visual Perception
  • Phototransduction
  • Positive Regulation Of CGMP-mediated Signaling
  • Regulation Of Rhodopsin Mediated Signaling Pathway
  • Positive Regulation Of Guanylate Cyclase Activity
  • Cellular Response To Calcium Ion
Pathways
  • Inactivation, recovery and regulation of the phototransduction cascade
Drugs
  • Myristic acid
Diseases
  • Cone-rod dystrophy and cone dystrophy, including: Cone-rod dystrophy (CORD); Cone dystrophy (COD); Retinal cone dystrophy (RCD)
GWAS
  • Spatial processing ( 31596458)
Novel Interacting Genes 1 novel interacting genes: BCKDK
Interacting Genes 9 interacting genes: AGR2 C1QTNF5 DDIT4L DEFB118 GSC2 GUCY2D HSPB1 KATNAL1 PRKAR1B
Entrez ID 2978
HPRD ID 02648
Ensembl ID ENSG00000048545
Uniprot IDs B2R9P6 P43080
PDB IDs
Enriched GO Terms of Interacting Partners?
Tagcloud ?

© Madhavi K. Ganapathiraju 2012-2025