DROSHA

Description		drosha ribonuclease III
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GO Annotations	Cellular Component	Nucleus Nucleoplasm Nucleolus Cytosol Postsynaptic Density Microprocessor Complex
	Molecular Function	Lipopolysaccharide Binding RNA Binding Double-stranded RNA Binding Ribonuclease III Activity Protein Binding DEAD/H-box RNA Helicase Binding Protein Homodimerization Activity SMAD Binding Metal Ion Binding R-SMAD Binding Primary MiRNA Binding
	Biological Process	RNA Processing MiRNA Metabolic Process Positive Regulation Of Gene Expression RRNA Catabolic Process Production Of SiRNA Involved In RNA Interference Primary MiRNA Processing Pre-miRNA Processing Ribosome Biogenesis Regulation Of Regulatory T Cell Differentiation Regulation Of Inflammatory Response Defense Response To Gram-negative Bacterium Defense Response To Gram-positive Bacterium RNA Phosphodiester Bond Hydrolysis, Endonucleolytic Regulation Of MiRNA Metabolic Process
Pathways		MicroRNA (miRNA) biogenesis
Drugs
Diseases
GWAS		Cerebrospinal fluid t-tau levels in Alzheimer's disease dementia ( 29274321) Lung function (FEV1) ( 26635082) Tuberculosis ( 30713548)
Interacting Genes		4 interacting genes: DGCR8 SP1 TULP3 ZNF512B
Entrez ID		29102
HPRD ID		10196
Ensembl ID		ENSG00000113360
Uniprot IDs		Q9NRR4
PDB IDs		2KHX 2NA2 5B16 6LXD 6LXE 6V5B 6V5C
Enriched GO Terms of Interacting Partners?
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