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GATA2
Description
GATA binding protein 2
Image
GO Annotations
Cellular Component
Nucleus
Nucleoplasm
Transcription Regulator Complex
Cytoplasm
Molecular Function
RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding
DNA-binding Transcription Factor Activity, RNA Polymerase II-specific
DNA-binding Transcription Activator Activity, RNA Polymerase II-specific
Chromatin Binding
DNA-binding Transcription Factor Activity
Protein Binding
Transcription Factor Binding
Zinc Ion Binding
C2H2 Zinc Finger Domain Binding
Sequence-specific Double-stranded DNA Binding
Biological Process
Urogenital System Development
Cell Fate Determination
Neuron Migration
Embryonic Placenta Development
Regulation Of Transcription By RNA Polymerase II
Phagocytosis
Positive Regulation Of Cytosolic Calcium Ion Concentration
Blood Coagulation
Positive Regulation Of Gene Expression
Negative Regulation Of Gene Expression
Regulation Of Primitive Erythrocyte Differentiation
Ventral Spinal Cord Interneuron Differentiation
Cell Differentiation In Hindbrain
Commitment Of Neuronal Cell To Specific Neuron Type In Forebrain
Central Nervous System Neuron Development
Pituitary Gland Development
Response To Lipid
Somatic Stem Cell Population Maintenance
Regulation Of Histone Acetylation
Eosinophil Fate Commitment
Inner Ear Morphogenesis
Positive Regulation Of Mast Cell Degranulation
Positive Regulation Of Blood Vessel Endothelial Cell Migration
Cell Fate Commitment
Negative Regulation Of Fat Cell Differentiation
Positive Regulation Of Erythrocyte Differentiation
Negative Regulation Of Macrophage Differentiation
Positive Regulation Of Megakaryocyte Differentiation
Positive Regulation Of Neuron Differentiation
Negative Regulation Of Notch Signaling Pathway
Positive Regulation Of Angiogenesis
Positive Regulation Of Transcription By RNA Polymerase II
Cell Maturation
Homeostasis Of Number Of Cells Within A Tissue
Positive Regulation Of Phagocytosis
Positive Regulation Of Phagocytosis, Engulfment
Definitive Hemopoiesis
Semicircular Canal Development
Vascular Wound Healing
Negative Regulation Of Fat Cell Proliferation
Positive Regulation Of Cell Migration Involved In Sprouting Angiogenesis
Cochlea Development
GABAergic Neuron Differentiation
Regulation Of Hematopoietic Stem Cell Differentiation
Positive Regulation Of Pri-miRNA Transcription By RNA Polymerase II
Positive Regulation Of Blood Vessel Endothelial Cell Proliferation Involved In Sprouting Angiogenesis
Negative Regulation Of Neural Precursor Cell Proliferation
Negative Regulation Of Endothelial Cell Apoptotic Process
Regulation Of Forebrain Neuron Differentiation
Pathways
RUNX1 regulates transcription of genes involved in differentiation of HSCs
Transcriptional regulation of granulopoiesis
Factors involved in megakaryocyte development and platelet production
Drugs
Diseases
GWAS
Basophil count (
28031487
)
Chronic obstructive pulmonary disease or high blood pressure (pleiotropy) (
30940143
)
Diastolic blood pressure (
30578418
)
Eosinophil counts (
19198610
)
Lymphocyte counts (
32888494
)
Lymphocyte percentage of white cells (
32888494
27863252
)
Monocyte count (
32888494
)
Monocyte percentage of white cells (
32888494
)
Myeloproliferative neoplasms (
33057200
)
Neutrophil count (
32888494
)
Neutrophil percentage of white cells (
32888494
27863252
)
Plateletcrit (
32888494
)
Preterm birth (maternal effect) (
28877031
)
Prostate cancer (
31562322
)
Pulse pressure (
28135244
27841878
30578418
)
Systolic blood pressure (
27841878
)
White blood cell count (
21738480
)
White blood cell count (basophil) (
28158719
)
White blood cell count (eosinophil) (
28158719
)
White blood cell types (
21738478
)
Interacting Genes
46 interacting genes:
ADAMTSL4
AKT1
CDK1
CEBPA
CYSRT1
EP300
FBXW7
FHL3
GOLGA2
HDAC3
HDAC5
HHEX
JUN
KAT2A
KRT40
KRTAP10-3
KRTAP10-9
KRTAP11-1
KRTAP13-3
KRTAP21-2
KRTAP3-1
KRTAP6-3
KRTAP7-1
KRTAP8-1
LMO2
MAPK1
MDFI
MSX2
NOTCH2NLA
PML
POU1F1
POU2AF1
PRR20A
PSMA3
RARA
RBPMS
RXRA
SMAD4
SPI1
STAT3
TAL1
TRAF1
TRIM23
ZBTB16
ZBTB32
ZFPM1
Entrez ID
2624
HPRD ID
00673
Ensembl ID
ENSG00000179348
Uniprot IDs
P23769
PDB IDs
5O9B
Enriched GO Terms of Interacting Partners
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