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PTPN23

Description protein tyrosine phosphatase non-receptor type 23
Image
GO Annotations Cellular Component
  • Nucleus
  • Nucleoplasm
  • Cytoplasm
  • Endosome
  • Early Endosome
  • Cytosol
  • Nuclear Body
  • Ciliary Basal Body
  • Intracellular Membrane-bounded Organelle
  • Extracellular Exosome
Molecular Function
  • Protein Tyrosine Phosphatase Activity
  • Protein Binding
  • Protein Kinase Binding
Biological Process
  • Negative Regulation Of Epithelial Cell Migration
  • Protein Transport
  • Endocytic Recycling
  • Peptidyl-tyrosine Dephosphorylation
  • Ubiquitin-dependent Protein Catabolic Process Via The Multivesicular Body Sorting Pathway
  • Early Endosome To Late Endosome Transport
  • Cilium Assembly
  • Positive Regulation Of Wnt Protein Secretion
  • Cellular Response To Cytokine Stimulus
  • Positive Regulation Of Homophilic Cell Adhesion
  • Positive Regulation Of Adherens Junction Organization
  • Positive Regulation Of Early Endosome To Late Endosome Transport
Pathways
  • Interleukin-37 signaling
Drugs
Diseases
GWAS
  • C-reactive protein levels ( 30388399)
  • Refractive error ( 32231278)
  • Type 2 diabetes (adjusted for BMI) ( 29632382)
Interacting Genes 11 interacting genes: ALG2 CEP19 CEP55 CHMP4B DDX24 LRRK2 NOTCH2NLA PSMA3 TRIM27 UBAP1 UBC
Entrez ID 25930
HPRD ID 05959
Ensembl ID ENSG00000076201
Uniprot IDs B4DST5 Q9H3S7
PDB IDs 3RAU 5CRU 5CRV 5LM1 5LM2 5MJY 5MJZ 5MK0 5MK1 5MK2 5MK3
Enriched GO Terms of Interacting Partners?
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© Madhavi K. Ganapathiraju 2012-2025