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POLR1A

Description RNA polymerase I subunit A
Image No pdb structure
GO Annotations Cellular Component
  • Nucleoplasm
  • Chromosome
  • RNA Polymerase I Complex
Molecular Function
  • RNA Polymerase I Activity
  • DNA Binding
  • Chromatin Binding
  • DNA-directed 5'-3' RNA Polymerase Activity
  • Protein Binding
  • Zinc Ion Binding
Biological Process
  • Transcription Initiation From RNA Polymerase I Promoter
  • Transcription Elongation From RNA Polymerase I Promoter
  • Termination Of RNA Polymerase I Transcription
  • Positive Regulation Of Gene Expression, Epigenetic
  • Negative Regulation Of Protein Localization To Nucleolus
Pathways
  • NoRC negatively regulates rRNA expression
  • B-WICH complex positively regulates rRNA expression
  • RNA Polymerase I Transcription Initiation
  • RNA Polymerase I Transcription Initiation
  • RNA Polymerase I Promoter Escape
  • RNA Polymerase I Transcription Termination
Drugs
Diseases
GWAS
  • Facial emotion recognition (sad faces) ( 28608620)
Novel Interacting Genes 1 novel interacting genes: TNFRSF14
Interacting Genes 10 interacting genes: ANP32B DYDC2 MEOX2 NFKBIB NOLC1 POLR1E PTEN REL RRN3 TCF4
Entrez ID 25885
HPRD ID 10161
Ensembl ID ENSG00000068654
Uniprot IDs O95602
PDB IDs
Enriched GO Terms of Interacting Partners?
Tagcloud ?

© Madhavi K. Ganapathiraju 2012-2025