GABRB3

Description		gamma-aminobutyric acid type A receptor subunit beta3
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GO Annotations	Cellular Component	Plasma Membrane Integral Component Of Plasma Membrane Cytoplasmic Vesicle Membrane Chloride Channel Complex Neuron Projection Synapse Postsynaptic Membrane GABA-A Receptor Complex
	Molecular Function	GABA-A Receptor Activity Chloride Channel Activity GABA-gated Chloride Ion Channel Activity Neurotransmitter Receptor Activity Identical Protein Binding
	Biological Process	Signal Transduction Gamma-aminobutyric Acid Signaling Pathway Chemical Synaptic Transmission Ion Transmembrane Transport Regulation Of Membrane Potential Nervous System Process Roof Of Mouth Development Cellular Response To Histamine Chloride Transmembrane Transport Inhibitory Synapse Assembly
Pathways		Signaling by ERBB4 GABA receptor activation GABA receptor activation
Drugs		Lorazepam Ethchlorvynol Enflurane Temazepam Butabarbital Butalbital Phenytoin Etomidate Talbutal Pentobarbital Clobazam Meprobamate Eszopiclone Alprazolam Lindane Metharbital Chlordiazepoxide Amoxapine Adinazolam Lamotrigine Piperazine Ivermectin Medroxyprogesterone acetate Clorazepic acid Acamprosate Midazolam Flurazepam Isoflurane Primidone Halazepam Propofol Propofol Diazepam Oxazepam Triazolam Ethanol Methoxyflurane Memantine Clonazepam Methyprylon Halothane Desflurane Flumazenil Estazolam Sevoflurane Glutethimide Camazepam Delorazepam Flunitrazepam Ethyl loflazepate Cloxazolam Bromazepam Clotiazepam Fludiazepam Ketazolam Prazepam Quazepam Cinolazepam Nitrazepam Prasterone Taurine Fospropofol Brotizolam Stiripentol Etizolam Thiocolchicoside Brexanolone Apalutamide Remimazolam Muscimol Benzodiazepine Pinazepam Medazepam Loprazolam Doxefazepam Lormetazepam Nordazepam Oxazepam acetate Cinazepam Bentazepam Mexazolam
Diseases
GWAS		Body mass index ( 28892062) Cognitive performance ( 19734545) Gut microbiota (bacterial taxa, hurdle binary method) ( 32572223) Longevity ( 20834067) Pericalcarine cortex volume ( 31530798) Postprandial triglyceride response ( 32603185) Refractive error ( 32231278) Response to methotrexate in juvenile idiopathic arthritis ( 24709693) Spontaneous preterm birth without premature rupture of membranes ( 31194736) Thyroglobulin plasma levels ( 30929638)
Interacting Genes		8 interacting genes: AKAP5 ARFGEF2 MEOX2 PPP2CA PRKACA PRKCA RACK1 UBQLN1
Entrez ID		2562
HPRD ID		08844
Ensembl ID		ENSG00000166206
Uniprot IDs		B2RCW8 P28472 X5DQY4
PDB IDs		4COF 5O8F 5OJM 6A96 6HUG 6HUJ 6HUK 6HUO 6HUP 6I53
Enriched GO Terms of Interacting Partners?
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