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NLRP1

Description NLR family pyrin domain containing 1
Image
GO Annotations Cellular Component
  • Nucleus
  • Nucleoplasm
  • Cytosol
  • Inflammasome Complex
  • NLRP1 Inflammasome Complex
Molecular Function
  • Protein Binding
  • ATP Binding
  • Cysteine-type Endopeptidase Activator Activity Involved In Apoptotic Process
  • Enzyme Binding
  • Protein Domain Specific Binding
Biological Process
  • Apoptotic Process
  • Activation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process
  • Inflammatory Response
  • Viral Process
  • Response To Muramyl Dipeptide
  • Positive Regulation Of Interleukin-1 Beta Production
  • Defense Response To Bacterium
  • Regulation Of Apoptotic Process
  • Regulation Of Inflammatory Response
  • Neuron Apoptotic Process
  • Defense Response To Virus
  • Pyroptosis
  • Self Proteolysis
  • Antiviral Innate Immune Response
  • NLRP1 Inflammasome Complex Assembly
Pathways
  • The NLRP1 inflammasome
Drugs
Diseases
GWAS
  • Migraine ( 27322543)
Interacting Genes 9 interacting genes: APAF1 BCL2 BCL2L1 CASP1 CASP2 CASP5 CASP9 NOD1 PYCARD
Entrez ID 22861
HPRD ID 07364
Ensembl ID ENSG00000091592
Uniprot IDs Q9C000
PDB IDs 1PN5 3KAT 4IFP 4IM6 5Y3S 6K7V
Enriched GO Terms of Interacting Partners?
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© Madhavi K. Ganapathiraju 2012-2025