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FGD1

Description FYVE, RhoGEF and PH domain containing 1
Image No pdb structure
GO Annotations Cellular Component
  • Ruffle
  • Cytoplasm
  • Golgi Apparatus
  • Cytosol
  • Cytoskeleton
  • Lamellipodium
Molecular Function
  • Guanyl-nucleotide Exchange Factor Activity
  • Small GTPase Binding
  • Metal Ion Binding
Biological Process
  • Cytoskeleton Organization
  • Signal Transduction
  • G Protein-coupled Receptor Signaling Pathway
  • Multicellular Organism Development
  • Regulation Of Cell Shape
  • Animal Organ Morphogenesis
  • Actin Cytoskeleton Organization
  • Positive Regulation Of Apoptotic Process
  • Regulation Of GTPase Activity
  • Filopodium Assembly
  • Regulation Of Small GTPase Mediated Signal Transduction
Pathways
  • NRAGE signals death through JNK
  • Rho GTPase cycle
  • G alpha (12/13) signalling events
Drugs
Diseases
  • Aarskog-Scott syndrome; Faciogenital dysplasia
GWAS
  • Prostate cancer ( 31562322)
Interacting Genes 5 interacting genes: AOC1 CDC42 CTTN ELMO1 SH3RF1
Entrez ID 2245
HPRD ID 02373
Ensembl ID ENSG00000102302
Uniprot IDs A0A024R9Y5 P98174
PDB IDs
Enriched GO Terms of Interacting Partners?
Tagcloud ?

© Madhavi K. Ganapathiraju 2012-2025