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RFX6
Description
regulatory factor X6
Image
No pdb structure
GO Annotations
Cellular Component
Chromatin
Nucleus
Molecular Function
Transcription Regulatory Region Sequence-specific DNA Binding
RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding
RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding
DNA-binding Transcription Factor Activity, RNA Polymerase II-specific
DNA-binding Transcription Activator Activity, RNA Polymerase II-specific
Protein Binding
Biological Process
Type B Pancreatic Cell Differentiation
Pancreatic A Cell Differentiation
Pancreatic D Cell Differentiation
Regulation Of Transcription By RNA Polymerase II
Endocrine Pancreas Development
Positive Regulation Of Insulin Secretion Involved In Cellular Response To Glucose Stimulus
Glucose Homeostasis
Positive Regulation Of Transcription, DNA-templated
Positive Regulation Of Transcription By RNA Polymerase II
Regulation Of Insulin Secretion
Pancreatic Epsilon Cell Differentiation
Pathways
Regulation of gene expression in beta cells
Drugs
Diseases
GWAS
Apolipoprotein A1 levels (
32203549
)
Chronic obstructive pulmonary disease (
30804561
)
Creatine kinase levels (
29403010
)
Diastolic blood pressure (
27841878
)
Eosinophil counts (
32888494
)
Eosinophil percentage of white cells (
32888494
)
Height (
31562340
)
Inflammatory bowel disease (
27569725
)
Lung cancer (
28604730
)
Neutrophil percentage of granulocytes (
27863252
)
Offspring birth weight (
31043758
)
Prostate cancer (
20676098
31562322
26443449
)
Serum total protein level (
29403010
)
Interacting Genes
41 interacting genes:
AGXT
ARNT2
CATSPER1
CCNK
CSTF2
CYFIP1
DGCR6
DMRT3
DTX2
DUSP21
ESR2
FHL3
FRS3
HGS
KCTD9
KIF1A
LGALS4
LMO3
MEMO1
NEDD9
PATZ1
PITX1
PLEKHN1
PPP1R32
PRKAA1
PRKAA2
RFX2
RFX3
RIPK3
SNRPB
SNRPC
SS18L1
STK16
TEKT3
TEKT4
TENT5B
TLE5
USP2
VPS37C
ZMYND19
ZNF688
Entrez ID
222546
HPRD ID
11490
Ensembl ID
ENSG00000185002
Uniprot IDs
Q8HWS3
PDB IDs
Enriched GO Terms of Interacting Partners
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