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GSDME

Description gasdermin E
Image No pdb structure
GO Annotations Cellular Component
  • Cytosol
  • Plasma Membrane
  • Membrane
  • Integral Component Of Membrane
Molecular Function
  • Protein Binding
  • Phosphatidylinositol-4,5-bisphosphate Binding
  • Cardiolipin Binding
Biological Process
  • Sensory Perception Of Sound
  • Cell Death
  • Negative Regulation Of Cell Population Proliferation
  • Positive Regulation Of MAPK Cascade
  • Inner Ear Receptor Cell Differentiation
  • Necrotic Cell Death
  • Pyroptosis
  • Cellular Response To Tumor Necrosis Factor
  • Cellular Response To Virus
  • Positive Regulation Of Intrinsic Apoptotic Signaling Pathway
Pathways
Drugs
Diseases
  • Deafness, autosomal dominant
GWAS
Novel Interacting Genes 8 novel interacting genes: AHR C1GALT1 GARS1 GP1BB GPNMB HNRNPA2B1 TBX19 VPS41
Interacting Genes 3 interacting genes: ITGB1BP1 PTN TIFA
Entrez ID 1687
HPRD ID 02996
Ensembl ID ENSG00000105928
Uniprot IDs A0A024RA58 A4FVA8 O60443
PDB IDs
Enriched GO Terms of Interacting Partners?
Tagcloud ?

© Madhavi K. Ganapathiraju 2012-2025