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ADSL

Description adenylosuccinate lyase
Image
GO Annotations Cellular Component
  • Cytosol
  • Protein-containing Complex
Molecular Function
  • N6-(1,2-dicarboxyethyl)AMP AMP-lyase (fumarate-forming) Activity
  • Identical Protein Binding
  • (S)-2-(5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamido)succinate AMP-lyase (fumarate-forming) Activity
Biological Process
  • Purine Nucleotide Biosynthetic Process
  • AMP Biosynthetic Process
  • 'de Novo' IMP Biosynthetic Process
  • Purine Ribonucleoside Monophosphate Biosynthetic Process
  • 'de Novo' AMP Biosynthetic Process
Pathways
  • Purine ribonucleoside monophosphate biosynthesis
Drugs
Diseases
  • Adenylosuccinate lyase deficiency
GWAS
  • Body mass index ( 26426971)
  • Height ( 19570815)
  • Regular attendance at a pub or social club ( 29970889)
Interacting Genes 3 interacting genes: CALCOCO2 CCN3 REL
Entrez ID 158
HPRD ID 00049
Ensembl ID ENSG00000239900
Uniprot IDs P30566 X5D7W4 X5D8S6
PDB IDs 2J91 2VD6 4FFX 4FLC
Enriched GO Terms of Interacting Partners?
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© Madhavi K. Ganapathiraju 2012-2025