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ESCO2

Description establishment of sister chromatid cohesion N-acetyltransferase 2
Image No pdb structure
GO Annotations Cellular Component
  • Chromatin
  • XY Body
  • Nucleoplasm
  • Chromosome
  • Pericentric Heterochromatin
  • Golgi Apparatus
  • Chromocenter
  • Cell Junction
  • Site Of Double-strand Break
Molecular Function
  • Lysine N-acetyltransferase Activity, Acting On Acetyl Phosphate As Donor
  • Protein Binding
  • Acetyltransferase Activity
  • Metal Ion Binding
Biological Process
  • Hematopoietic Progenitor Cell Differentiation
  • Regulation Of DNA Replication
  • Double-strand Break Repair
  • Sister Chromatid Cohesion
  • Post-translational Protein Acetylation
  • Protein Localization To Chromatin
Pathways
  • Establishment of Sister Chromatid Cohesion
Drugs
Diseases
  • ESCO2-related disorders, including: Roberts syndrome; SC phocomelia syndrome
GWAS
Interacting Genes 12 interacting genes: FXR1 GOLGA2 MCM2 MCM4 MCM5 MCM6 MCM7 MMS22L PCNA PICK1 RABEP1 SMC3
Entrez ID 157570
HPRD ID 18564
Ensembl ID ENSG00000171320
Uniprot IDs Q56NI9
PDB IDs
Enriched GO Terms of Interacting Partners?
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© Madhavi K. Ganapathiraju 2012-2025