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CTSV

Description cathepsin V
Image
GO Annotations Cellular Component
  • Extracellular Region
  • Extracellular Space
  • Lysosome
  • Lysosomal Lumen
Molecular Function
  • Cysteine-type Endopeptidase Activity
  • Protein Binding
  • Cysteine-type Peptidase Activity
Biological Process
  • Immune Response
  • Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class II
  • Extracellular Matrix Disassembly
  • Regulation Of Keratinocyte Differentiation
  • Proteolysis Involved In Cellular Protein Catabolic Process
Pathways
  • Endosomal/Vacuolar pathway
  • Degradation of the extracellular matrix
  • Activation of Matrix Metalloproteinases
  • Trafficking and processing of endosomal TLR
  • Assembly of collagen fibrils and other multimeric structures
  • MHC class II antigen presentation
  • RUNX1 regulates transcription of genes involved in differentiation of keratinocytes
Drugs
  • 3-amino-5-phenylpentane
  • 4-Methylpiperazin-1-Yl Carbonyl Group
Diseases
GWAS
Novel Interacting Genes 1 novel interacting genes: KCNJ1
Interacting Genes 13 interacting genes: APC BMPR1A BRAF BUB1 CDKN2A CTNNA1 DCC DLC1 MLH1 MLH3 PDGFRL RB1 SRC
Entrez ID 1515
HPRD ID 04495
Ensembl ID ENSG00000136943
Uniprot IDs A0A024R141 B2R717 O60911
PDB IDs 1FH0 3H6S 3KFQ
Enriched GO Terms of Interacting Partners?
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