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CSF3
Description
colony stimulating factor 3
Image
GO Annotations
Cellular Component
Extracellular Region
Extracellular Space
Molecular Function
Cytokine Activity
Granulocyte Colony-stimulating Factor Receptor Binding
Growth Factor Activity
Enzyme Binding
Biological Process
Immune Response
Multicellular Organism Development
Positive Regulation Of Cell Population Proliferation
Positive Regulation Of Phosphatidylinositol 3-kinase Signaling
Cytokine-mediated Signaling Pathway
Positive Regulation Of Actin Filament Polymerization
Granulocyte Differentiation
Positive Regulation Of Protein Binding
Positive Regulation Of Peptidyl-serine Phosphorylation
Response To Ethanol
Positive Regulation Of Myeloid Cell Differentiation
Positive Regulation Of Transcription By RNA Polymerase II
Positive Regulation Of Peptidyl-tyrosine Phosphorylation
Positive Regulation Of DNA-binding Transcription Factor Activity
Positive Regulation Of Protein Kinase B Signaling
Cellular Response To Lipopolysaccharide
Cellular Response To Cytokine Stimulus
Negative Regulation Of Neuron Death
Positive Regulation Of Actin Cytoskeleton Reorganization
Pathways
Other interleukin signaling
Interleukin-10 signaling
Drugs
Diseases
GWAS
Asthma (
31619474
)
Bipolar disorder (
31043756
)
Composite immunoglobulin trait (IgA x IgG) (
28628107
)
Creatine kinase levels (
29403010
)
Granulocyte count (
27863252
)
Granulocyte percentage of myeloid white cells (
27863252
)
Lymphocyte percentage of white cells (
32888494
27863252
)
Mitochondrial DNA copy number (
30704525
)
Myeloid white cell count (
27863252
)
Neutrophil count (
25096241
20172861
32888494
27863252
)
Neutrophil percentage of white cells (
32888494
27863252
)
Rheumatoid arthritis (
30423114
24390342
)
Sum basophil neutrophil counts (
27863252
)
Sum neutrophil eosinophil counts (
27863252
)
White blood cell count (
29403010
32888494
20139978
27863252
21738480
28158719
)
White blood cell count (neutrophil) (
28158719
)
White blood cell types (
21738478
)
Novel Interacting Genes
5 novel interacting genes:
CDK2
HDAC6
NOS2
NQO2
SLFN11
Interacting Genes
4 interacting genes:
CSF3R
ELANE
PARVG
TBX3
Entrez ID
1440
HPRD ID
00736
Ensembl ID
ENSG00000108342
Uniprot IDs
P09919
Q6FH65
Q8N4W3
PDB IDs
1CD9
1GNC
1PGR
1RHG
2D9Q
5GW9
5ZO6
Enriched GO Terms of Interacting Partners
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