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COMP
Description
cartilage oligomeric matrix protein
Image
GO Annotations
Cellular Component
Extracellular Region
Extracellular Space
Extracellular Matrix
Protein-containing Complex
Collagen-containing Extracellular Matrix
Extracellular Exosome
Molecular Function
Protease Binding
Integrin Binding
Extracellular Matrix Structural Constituent
Calcium Ion Binding
Protein Binding
Collagen Binding
Heparin Binding
BMP Binding
Proteoglycan Binding
Heparan Sulfate Proteoglycan Binding
Biological Process
Skeletal System Development
Chondrocyte Development
Growth Plate Cartilage Development
Apoptotic Process
Response To Unfolded Protein
Protein Secretion
Animal Organ Morphogenesis
Multicellular Organism Aging
Animal Organ Senescence
Regulation Of Gene Expression
Vascular Associated Smooth Muscle Contraction
Protein Processing
Extracellular Matrix Organization
Collagen Fibril Organization
Bone Mineralization
Regulation Of Bone Mineralization
BMP Signaling Pathway
Multicellular Organism Growth
Chondrocyte Proliferation
Tendon Development
Negative Regulation Of Apoptotic Process
Skin Development
Muscle Fiber Development
Artery Morphogenesis
Musculoskeletal Movement
Neuromuscular Process
Limb Development
Platelet Aggregation
Vascular Associated Smooth Muscle Cell Development
Negative Regulation Of Hemostasis
Positive Regulation Of Chondrocyte Proliferation
Pathways
Integrin cell surface interactions
ECM proteoglycans
Drugs
Calcium
Diseases
Pseudoachondroplasia (PSACH)
Multiple epiphyseal dysplasia (MED)
GWAS
Osteoarthritis (with total hip replacement) (
28319091
)
Osteoarthritis biomarkers (
25057126
)
QT interval (
29213071
)
Interacting Genes
10 interacting genes:
AQP1
ATOX1
COL2A1
COL9A1
CYSRT1
FN1
MEOX2
NUFIP2
OTX1
SGTB
Entrez ID
1311
HPRD ID
02632
Ensembl ID
ENSG00000105664
Uniprot IDs
P49747
PDB IDs
3FBY
Enriched GO Terms of Interacting Partners
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