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IQGAP3

Description IQ motif containing GTPase activating protein 3
Image
GO Annotations Cellular Component
  • Cytoplasm
  • Cytosol
  • Cell-cell Junction
  • Lateral Plasma Membrane
Molecular Function
  • GTPase Activator Activity
  • Protein Binding
  • Calmodulin Binding
  • Actin Filament Binding
  • Myosin VI Light Chain Binding
Biological Process
  • G1/S Transition Of Mitotic Cell Cycle
  • Activation Of MAPK Activity
  • Ras Protein Signal Transduction
  • Regulation Of Cell Size
  • Positive Regulation Of Gene Expression
  • Negative Regulation Of Gene Expression
  • Regulation Of Actin Cytoskeleton Organization
  • Positive Regulation Of Mammary Gland Epithelial Cell Proliferation
  • Positive Regulation Of GTPase Activity
  • ERK1 And ERK2 Cascade
  • Cellular Response To Organic Substance
Pathways
  • RHO GTPases activate IQGAPs
Drugs
Diseases
GWAS
  • Adult body size ( 32376654)
  • Creatine kinase levels ( 29403010)
Interacting Genes 2 interacting genes: CALM2 CCDC198
Entrez ID 128239
HPRD ID 11051
Ensembl ID ENSG00000183856
Uniprot IDs Q86VI3
PDB IDs 3ISU
Enriched GO Terms of Interacting Partners?
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© Madhavi K. Ganapathiraju 2012-2025