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SPINT2

Description serine peptidase inhibitor, Kunitz type 2
Image
GO Annotations Cellular Component
  • Extracellular Region
  • Cytoplasm
  • Plasma Membrane
  • Integral Component Of Membrane
Molecular Function
  • Endopeptidase Inhibitor Activity
  • Serine-type Endopeptidase Inhibitor Activity
Biological Process
  • Neural Tube Closure
  • Establishment Or Maintenance Of Cell Polarity
  • Negative Regulation Of Endopeptidase Activity
  • Negative Regulation Of Cell-cell Adhesion
  • Epithelial Cell Morphogenesis Involved In Placental Branching
  • Basement Membrane Organization
  • Cellular Response To BMP Stimulus
  • Negative Regulation Of Cell Motility
  • Negative Regulation Of Neural Precursor Cell Proliferation
Pathways
  • MET Receptor Activation
  • Signaling by MST1
Drugs
Diseases
GWAS
  • Blood protein levels ( 30072576 29875488)
  • Platelet count ( 32888494 27863252)
  • Platelet distribution width ( 32888494)
Interacting Genes 6 interacting genes: APP CTSB HGFAC ITIH2 ITIH3 SUMO4
Entrez ID 10653
HPRD ID 05495
Ensembl ID ENSG00000167642
Uniprot IDs A0A140VJV6 O43291
PDB IDs 4U32
Enriched GO Terms of Interacting Partners?
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© Madhavi K. Ganapathiraju 2012-2025