ERN2

Description		endoplasmic reticulum to nucleus signaling 2
Image		No pdb structure
GO Annotations	Cellular Component	Integral Component Of Membrane Endoplasmic Reticulum Quality Control Compartment IRE1-TRAF2-ASK1 Complex
	Molecular Function	Magnesium Ion Binding Endonuclease Activity Endoribonuclease Activity Protein Serine/threonine Kinase Activity ATP Binding Unfolded Protein Binding Protein Serine Kinase Activity Protein Threonine Kinase Activity
	Biological Process	MRNA Processing Protein Phosphorylation Cell Cycle Arrest Activation Of JUN Kinase Activity RRNA Catabolic Process Apoptotic Chromosome Condensation Response To Endoplasmic Reticulum Stress IRE1-mediated Unfolded Protein Response Negative Regulation Of Transcription, DNA-templated Intrinsic Apoptotic Signaling Pathway In Response To Endoplasmic Reticulum Stress RNA Phosphodiester Bond Hydrolysis, Endonucleolytic
Pathways
Drugs
Diseases
GWAS
Novel Interacting Genes		1 novel interacting genes: IL4R
Interacting Genes
Entrez ID		10595
HPRD ID		04944
Ensembl ID		ENSG00000134398
Uniprot IDs		A5YM46 A5YM65 E7ETG2 Q76MJ5
PDB IDs
Enriched GO Terms of Interacting Partners?
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