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CEACAM5

Description CEA cell adhesion molecule 5
Image
GO Annotations Cellular Component
  • Extracellular Region
  • Plasma Membrane
  • Integral Component Of Plasma Membrane
  • Cell Surface
  • Basolateral Plasma Membrane
  • Apical Plasma Membrane
  • Anchored Component Of Membrane
  • Extracellular Exosome
  • Integral Component Of External Side Of Plasma Membrane
Molecular Function
  • Protein Binding
  • GPI Anchor Binding
  • Identical Protein Binding
  • Protein Homodimerization Activity
Biological Process
  • Apoptotic Process
  • Homophilic Cell Adhesion Via Plasma Membrane Adhesion Molecules
  • Heterophilic Cell-cell Adhesion Via Plasma Membrane Cell Adhesion Molecules
  • Negative Regulation Of Myotube Differentiation
  • Homotypic Cell-cell Adhesion
  • Negative Regulation Of Apoptotic Process
  • Leukocyte Migration
  • Negative Regulation Of Anoikis
Pathways
  • Post-translational modification: synthesis of GPI-anchored proteins
  • Cell surface interactions at the vascular wall
Drugs
  • Labetuzumab
  • S-[(1-Hydroxy-2,2,5,5-tetramethyl-2,5-dihydro-1H-pyrrol-3-yl)methyl] methanesulfonothioate
Diseases
GWAS
  • Epstein-Barr virus copy number in lymphoblastoid cell lines ( 28654678)
  • Serum carcinoembryonic antigen levels ( 31666285)
Novel Interacting Genes 1 novel interacting genes: IMPDH2
Interacting Genes 6 interacting genes: CEACAM1 CEACAM6 DISP3 EWSR1 HNRNPM UQCC2
Entrez ID 1048
HPRD ID 00274
Ensembl ID ENSG00000105388
Uniprot IDs A0A024R0K5 P06731 Q53G30
PDB IDs 1E07 2QSQ 2QST 2VER
Enriched GO Terms of Interacting Partners?
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© Madhavi K. Ganapathiraju 2012-2025