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KLF2
Description
Kruppel like factor 2
Image
No pdb structure
GO Annotations
Cellular Component
Chromatin
Nucleus
Molecular Function
RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding
DNA-binding Transcription Factor Activity, RNA Polymerase II-specific
DNA Binding
DNA-binding Transcription Factor Activity
Protein Binding
Metal Ion Binding
Sequence-specific Double-stranded DNA Binding
Biological Process
Negative Regulation Of Transcription By RNA Polymerase II
Cell Morphogenesis
In Utero Embryonic Development
Regulation Of Transcription By RNA Polymerase II
Negative Regulation Of Interleukin-6 Production
Multicellular Organism Growth
Positive Regulation Of Transcription From RNA Polymerase II Promoter In Response To Stress
Regulation Of Gene Expression, Epigenetic
Vasodilation
Erythrocyte Maturation
Positive Regulation Of Nitric Oxide Biosynthetic Process
Positive Regulation Of Transcription, DNA-templated
Positive Regulation Of Transcription By RNA Polymerase II
Positive Regulation Of Retinoic Acid Receptor Signaling Pathway
Positive Regulation Of Protein Metabolic Process
Type I Pneumocyte Differentiation
Cellular Response To Hydrogen Peroxide
Cellular Response To Interleukin-1
Cellular Response To Tumor Necrosis Factor
Cellular Response To Cycloheximide
Cellular Response To Fluid Shear Stress
Cellular Response To Laminar Fluid Shear Stress
Cellular Stress Response To Acid Chemical
Cellular Response To Peptide
Negative Regulation Of Sprouting Angiogenesis
Pathways
Drugs
Diseases
GWAS
Asthma (
32296059
)
Coronary artery disease (
33020668
)
Depression in smokers (
30219690
)
Diastolic blood pressure (
30224653
)
Eosinophil counts (
32888494
)
Eosinophil percentage of white cells (
32888494
)
Heel bone mineral density (
30598549
)
Lymphocyte counts (
32888494
27863252
)
Lymphocyte percentage of white cells (
32888494
27863252
)
Monocyte count (
32888494
)
Neutrophil percentage of white cells (
32888494
)
White blood cell count (
32888494
)
Interacting Genes
7 interacting genes:
EP300
GATA5
GATA6
GSK3B
KAT2B
PSME3
WWP1
Entrez ID
10365
HPRD ID
03602
Ensembl ID
ENSG00000127528
Uniprot IDs
Q9Y5W3
PDB IDs
Enriched GO Terms of Interacting Partners
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