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ALG3

Description ALG3 alpha-1,3- mannosyltransferase
Image No pdb structure
GO Annotations Cellular Component
  • Endoplasmic Reticulum
  • Endoplasmic Reticulum Membrane
  • Integral Component Of Membrane
Molecular Function
  • Alpha-1,3-mannosyltransferase Activity
  • Protein Binding
  • Dol-P-Man:Man(5)GlcNAc(2)-PP-Dol Alpha-1,3-mannosyltransferase Activity
Biological Process
  • Protein Glycosylation
  • Dolichol-linked Oligosaccharide Biosynthetic Process
  • Mannosylation
Pathways
  • Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein
  • Defective ALG3 causes ALG3-CDG (CDG-1d)
Drugs
Diseases
  • Congenital disorders of glycosylation (CDG) type I
GWAS
  • Major depressive disorder ( 22472876)
Interacting Genes 7 interacting genes: ARL13B CD79A CREB3 LMNA SERP1 SSMEM1 TMEM52B
Entrez ID 10195
HPRD ID 03067
Ensembl ID ENSG00000214160
Uniprot IDs C9J7S5 Q92685
PDB IDs
Enriched GO Terms of Interacting Partners?
Tagcloud ?

© Madhavi K. Ganapathiraju 2012-2025