FAM13A

Description		family with sequence similarity 13 member A
Image		No pdb structure
GO Annotations	Cellular Component	Cytosol
	Molecular Function	GTPase Activator Activity
	Biological Process	Signal Transduction Positive Regulation Of GTPase Activity Regulation Of Small GTPase Mediated Signal Transduction
Pathways		Rho GTPase cycle
Drugs
Diseases
GWAS		Adiponectin levels ( 31178129) Apolipoprotein A1 levels ( 32203549) Chronic bronchitis and chronic obstructive pulmonary disease ( 25241909) Chronic obstructive pulmonary disease ( 25241909 22080838 28166215 30804561 25101718 20173748) Chronic obstructive pulmonary disease (moderate to severe) ( 24621683) Chronic obstructive pulmonary disease (severe) ( 24621683) Chronic obstructive pulmonary disease or high blood pressure (pleiotropy) ( 30940143) Hair greying ( 26926045) HDL cholesterol ( 24097068 30275531) HDL cholesterol levels ( 32203549 28334899) Hematocrit ( 32888494) Hemoglobin ( 32888494) Idiopathic pulmonary fibrosis ( 31710517) Insular cortex volume ( 31530798) Interstitial lung disease ( 23583980) Left-handedness ( 32989287) Longevity ( 26912274) Lung function ( 31902109) Lung function (FEV1/FVC) ( 28166213 30804560) Lung function (FVC) ( 30804560) Mean platelet volume ( 32888494) Peak expiratory flow ( 30804560) Post bronchodilator FEV1 ( 26634245) Post bronchodilator FEV1/FVC ratio ( 26634245) Pre bronchodilator FEV1/FVC ratio in never-smokers ( 27612410) Pulmonary function ( 20010835) Pulmonary function (smoking interaction) ( 23284291) Pulse pressure ( 27841878) Red blood cell count ( 32888494) Refractive error ( 32231278) Systolic blood pressure ( 27841878 30578418) Triglyceride levels ( 32203549 32154731) Type 2 diabetes ( 30297969) Urate levels ( 31578528) Waist-to-hip ratio adjusted for BMI ( 26426971) Waist-to-hip ratio adjusted for BMI (additive genetic model) ( 30778226) Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour) ( 28443625) Waist-to-hip ratio adjusted for BMI (age <50) ( 26426971) Waist-to-hip ratio adjusted for BMI (joint analysis main effects and smoking interaction) ( 28443625) Waist-to-hip ratio adjusted for BMI in non-smokers ( 28443625) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971) Waist-to-hip ratio adjusted for body mass index ( 25673412 28430825)
Interacting Genes		1 interacting genes: RAC1
Entrez ID		10144
HPRD ID		10944
Ensembl ID		ENSG00000138640
Uniprot IDs		O94988
PDB IDs
Enriched GO Terms of Interacting Partners?
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